Common name:

Japanese Knotweed



Parts used:

Rhizome, root


Resveratrol, trans-resveratrol, emodin, emodin monomethyl ether, polydatin (piceid), piceatannol, physcion, astringin, oxalic acid, rheic acid, barium, bromine, catechin, chrysophanol, itreosein, dimethylhyroxychromone, fallacinol, glucofragulin, isoquercitrin, manganese, methylcoumarin napthoquinone, physide, piceid, plastoquinone, polydatoside, polygonin, protocatechuic acid, quercitrin, questin, questinol, reynoutriin, rheic acid, rubidium, rutin, and numerous minerals, flavonoids, polysaccharides, and tannins.

Main actions:

Antibacterial, antiviral (HBV & HIV), antischistosomal, antispirochetal, antifungal, immunostimulant, immunomodulant, anti-inflammatory

Other Actions:

Antoxidant, antiatherosclerotic, antihyperlipidemic, antimutagenic, anticarcinogenic, antineoplastic, CNS protectant, neuroprotective, vasodilator, inhibitor of platelet aggregation, eicosanoid synthesis suppressant, antithrombotic, tyrosine kinase inhibitor (TNF-alpha), oncogene inhibitor, antipyretic, cardioprotective, mildly analgesic, antiulcer, antitumor,  hemostatic and astringent

TCM (Hu zhang)

Invigorates the qi and qi, stops pain

Clears heat, resolves toxins

Transforms phlegm, stops cough

Traditional uses

Arthritis, traumatic injury, jaundice, urinary disorders, constipation, menstrual disorders, kidney stones, burns, haemorrhoids, carbuncles, skin infections, snakebites, dental caries


Tincture: 1-3ml TID






Contraindicated in pregnancy

Can cause digestive complaints in high doses.



A Review of the Pharmacological Effects of the Dried Root of Polygonum cuspidatum (Hu Zhang) and Its ConstituentsEvidence-Based Complementary and Alternative Medicine

Volume 2013 (2013), Article ID 208349, 13 pages